PRP Is Not Associated With Improved Outcomes Following Hip Femoroacetabular Impingement Surgery: Very Low-Quality Evidence Suggests Hyaluronic Acid and Cell-Based Therapies May Be Beneficial - A Systematic Review of Biological Treatments
The use of and interest in biologic treatments has grown in popularity in sports medicine, however their efficacy remains ambiguous. The purpose of this systematic review was to examine the efficacy of biologic agents in the treatment of cartilage defects associated with femoroacetabular impingement (FAI). The results demonstrate low quality evidence to indicate that PRP as an adjuvant to surgery does not improve function or pain compared with surgery without PRP. Very low-quality evidence suggests hyaluronic acid (HA) improves pain and function in patients with FAI. Very low-quality evidence would also indicate cell-based treatments for cartilage defects can improve function and pain in hip surgery for FAI. Although HA and cell-based therapies may appear to improve symptoms, their efficacy should be viewed in light of the quality of evidence, and caution is advised.